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No specific dose adjustment encouraged when tofacitinib coadministered with potent CYP2C19 inhibitors; decrease tofacitinib dose if coadministered with each average CYP3A4 and potent CYP2C19 inhibitors .Keep track of Closely (one)modafinil will improve the level or influence of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.ribociclib w